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modular-bioreactor
  • Modular Bioreactor
  • System Description
  • Project Dashboard
  • V2 system specifications
    • GUI
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  • use cases
    • Use cases
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  • technical features
  • Incubator
  • Perfusion Tray
  • V1 Control Interface
  • V2 Control Interface
  • V2 Wiring Diagram
  • Testing
    • Cell culture tests
      • Materials biocompatibility tests
      • Peristaltic based perfusion system - layout
      • Peristaltic based perfusion system - results
      • Issues encountered
    • Usability testing
      • Temperature Distribution
      • CO2 Regulation
      • Humidity and water loss
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  1. Testing
  2. Cell culture tests

Materials biocompatibility tests

Providing information about materials' biocompatibility.

PreviousCell culture testsNextPeristaltic based perfusion system - layout

Last updated 4 years ago

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Little fragments of materials were put into tissue culture, which was then observed for 1 week.

  • Materials that proved safe for use with HUVECs (Human Umbilical Vein Endothelial Cells) and SFs (Skin Fibroblasts)

    • Polyether ether ketone - (PEEK) (also autoclaved)

    • Polyoxymethylene - (POM) - white, no pigment (not autoclaved!)

    • Polyoxymethylene - (POM) - black, pigmented (not autoclaved!)

    • Poly(methyl methacrylate) (acrylic glass - "pleksi steklo")

    • UV polymerized SLA resin "Formlabs Standard - Clear" ()

    • UV polymerized SLA resin "Formlabs Dental LT Clear" ()

    • UV polymerized SLA resin "W2P Solflex Ortho Clear" ()

    • UV polymerized SLA resin "Prima Creator DLP resin Standard" ()

    • PharMed® BPT Tubing (not yet tested with SFs)

  • Cytotoxic materials

    • none so far

https://formlabs.com/eu/materials/standard/#clear
https://dental.formlabs.com/eu/materials/#dental-lt-clear
https://www.way2production.at/wp-content/uploads/2018/10/Solflex-Ortho-Clear.pdf
https://primacreator.com/products/primacreator-value-uv-dlp-dlp-resin